Endocrine Abstracts

Introduction: Fahr’s syndrome and primary hypoparathyroidism are two rare diseases. Fahr’s syndrome is characterized by abnormal calcified deposits in basal ganglia and cerebral cortex and by the classic association with hypoparathyroidism. We report two cases of Fahr syndrome revealing an unknown primary hypoparathyroidism.Observation 1: A 36 year-old man, with a history of schizophrenia and generalized tonic-clonic seizures since two years. H...

Introduction: Fahr’s syndrome (SF) is a rare anatomo-clinical entity, defined by non-arteriosclerotic striato-pallido-serrated calcifications localized in basal ganglia. It may be idiopathic or secondary to many etiologies dominated by phosphocalcic metabolic abnormalities, the main cause being primary or postoperative hypoparathyroidism.Materials: This is a retrospective, descriptive study involving 11 patients with FAHR syndrome hospitalized at th...

Introduction: Therapeutic education (TE) on injection techniques and zooning is a key step for any insulin-treated patient. Our study’s objective was to evaluate the role of ET and the number of sessions required to prevent lipodystrophies (LD).Materials and methods: We conducted a prospective study including any diabetic insulin-treated patient for more than 6 months, followed in our unit between February 2015 and June 2017. Patients responded to a...

Introduction: A good injection technique is crucial to ensure that insulin is properly administered into the subcutaneous tissue and then released at the right time, to avoid some common complications such as lipodystrophies (LD). The objective of our study is to evaluate injection techniques in Moroccan diabetic patients.Materials and methods: We conducted a prospective study including any diabetic insulin-treated patient for more than 6 months, followe...

Introduction: Changing needles and syringes when injecting insulin is often included in recommendations on injection techniques and in education sessions. The objective of our study was to evaluate the rate of insulin needle reuse and its consequences.Materials and methods: We conducted a prospective study including any diabetic insulin-treated patient for more than 6 months, followed up at the service between February 2015 and June 2017. Patients respon...

Introduction: Given their prevalence of up to 5% of the general population, A discovery of an asymptomatic adrenal mass (incidentaloma) during the investigation of an unrelated condition is relatively common. The issue of crucial importance is the histopathological differentiation between benign lesions and malignant tumours of the adrenal gland.Objective: To evaluate the secretory or non-secretory profile and the benign and malignant nature of incidenta...

Introduction: Adrenal incidentalomas are frequent, their prevalence reaches 5% of the general population, incidental diagnosis from an imaging examination motivated by an extra-adrenal sign is common. Diabetes may be present in patients with adrenal incidentaloma, it is often diabetes secondary to secretion of cathecholamines, mineralocorticoids and cortisol.Objective: To evaluate the clinical-biological profile of adrenal incidentalomas, as well as thei...

Introduction: Von Hippel-Lindau disease (VHL) is a hereditary condition that predisposes to the development of benign and malignant tumors due to mutations in the VHL gene. Several clinical manifestations can be observed including the development of hemangioblastomas of the central nervous system and the retina, renal or pancreatic cysts or cancers, or more rarely pheochromocytomas. These affect 10 to 25% of patients, are frequently bilateral and often reveal the disease.<...

Introduction: Magnesium is the fourth most abundant cation in the body and plays an important physiological role in many of its functions. However, an association between hypomagnesemia and insulin resistance (IR) in diabetes has recently been found.Objective: To determine the correlation between hypomagnesemia, glycemic imbalance and the degenerative complications of type 2 diabetes.Materials and methods: We conducted a prospectiv...

Introduction: Corticosteroid-induced diabetes (CID) is a common and potentially harmful problem in clinical practice. Its pathophysiological mechanisms are multiple, from increased hepatic neoglucogenesis to peripheral insulin resistance or direct toxic effect on the β cell. The aim of our study was to study the clinical profile of patients who developed corticosteroid-induced diabetes and its factors of occurrence.Method: We report a retrospective ...